1. Describe the "Old View" of atherosclerosis.

2. What is the "worse-case" scenario of atherosclerosis?

3. Why do these problems (#2) occur?

4. What does current research suggest regarding the:
a. location of plaques
b. effects on blood flow

5. What molecule has been implicated as being responsible for the onset of atherosclerosis? Where does it initiate this problem?

6. How does concentration of LDL effect the onset of atherosclerosis?

7. Why does accumulated LDL cause problems when "free-floating" LDL is always present?

8. How is the inflammatory reaction causing atherosclerosis initiated?

9. What role do monocytes play in the inflammatory process? What is a foam cell?

10. What do T-cells do to enhance the inflammatory reaction?

11. Describe briefly the "healing process" with atherosclerotic inflammation.

12. Describe the effects stenosis may have on the heart and legs.

13. Only 15% of heart attacks are caused by stenosis. What causes the other 85%?

14. Blood clots are stimulated by what action? What precursors exist that may lead to clot formation?

15. What actions occur to create a clot?

16. How does a damaged plaque lead to an increase in a plaques size?

17. Describe other risk factors which may (can) promote atherosclerosis through interaction with LDL.

18. How does aspirin seem to work to prevent heart attacks?

19. Short of drug therapy, what can an individual do to lower the risk of heart attacks?

20. What is C-reactive protein and how can it be used to treat atherosclerosis?